American Journal of Preventive Medicine
Volume 28, Issue 1 , Pages 1-8 , January 2005

Exercise treatment for depression: Efficacy and dose response

  • Andrea L. Dunn, PhD

      Affiliations

    • Cooper Institute, Behavioral Science Research Center, Golden, Colorado
    • Corresponding Author InformationAddress correspondence and reprint requests to: Andrea L. Dunn, PhD, The Cooper Institute, Behavioral Science Research Center, 14023 Denver West Parkway, Suite 100, Golden CO 80401.
    • ,
  • Madhukar H. Trivedi, MD

      Affiliations

    • University of Texas Southwestern Medical Center, Depression and Anxiety Disorders Program, Dallas, Texas, USA
    • ,
  • James B. Kampert, PhD

      Affiliations

    • Cooper Institute, Centers for Integrated Health Research, Dallas, Texas
    • ,
  • Camillia G. Clark, PhD

      Affiliations

    • Alberta Children’s Hospital, Psychology Section, Calgary, Alberta, Canada
    • ,
  • Heather O. Chambliss, PhD

      Affiliations

    • Cooper Institute, Centers for Integrated Health Research, Dallas, Texas

References 

  1. Murray CJL , Lopez AD . Global mortality, disability, and the contribution of risk factors (Global Burden of Disease Study) . Lancet . 1997;349:1436–1442
  2. U.S. Department of Health and Human Services . Mental health (a report of the Surgeon General) . Rockville MD: U.S. Department of Health and Human Services, Substance Abuse and Mental Health Services Administration, Center for Mental Health Services, National Institutes of Health, National Institute of Mental Health; 1999;
  3. Robins LN , Regier DA . Psychiatric disorders in America (the Epidemiologic Catchment Area Study) . New York: Free Press; 1991;
  4. Rush AJ , Golden WE , Hall GW , et al.   Depression in primary care. Vol. 1, Detection and diagnosis . Clinical practice guideline, Number 5 . Rockville MD: U.S. Department of Health and Human Services, Public Health Service, Agency for Health Care Policy and Research; 1993;
  5. Rush AJ , Golden WE , Hall GW , et al.   Depression in primary care. Vol. 2, Treatment of major depression . Rockville MD: U.S. Department of Health and Human Services, Public Health Service, Agency for Health Care Policy and Research; 1993;
  6. Martinsen EW . The role of aerobic exercise in the treatment of depression . Stress Med . 1987;3:93–100
  7. Singh NA , Singh MAF . Exercise and depression in the older adult . Nutr Clin Care . 2000;3:197–208
  8. McNeil JK , LeBlanc EM , Joyner M . The effect of exercise on depressive symptoms in the moderately depressed elderly . Psychol Aging . 1991;6:487–488
  9. Greist JH , Klein MH , Eischens RR , Faris J , Gurman AS , Morgan WP . Running as treatment for depression . Comp Psychiatry . 1979;20:41–54
  10. Paffenbarger RS , Lee IM , Leung R . Physical activity and personal characteristics associated with depression and suicide in American college men . Acta Psychiatr Scand Suppl . 1994;377:16–22
  11. Blumenthal JA , Babyak MA , Moore KA , et al.   Effects of exercise training on older patients with major depression . Arch Intern Med . 1999;159:2349–2356
  12. Hamilton M . Development of a rating scale for depressive illness . Br J Soc Clin Psychol . 1968;6:278–296
  13. Knesevich JW , Biggs JT , Clayton PJ , Ziegler VE . Validity of the Hamilton Rating Scale for Depression . Br J Psychiatry . 1977;131:49–52
  14. Frank E , Prien RF , Jarrett RB , et al.   Conceptualization and rationale for consensus definitions of terms in major depressive disorder. remission, recovery, relapse, and recurrence . Arch Gen Psychiatry . 1991;48:851–855
  15. Dunn AL , Trivedi MH , Kampert JB , Clark CG , Chambliss HO . The DOSE study: exercise as treatment for depression: a clinical trial to examine efficacy and dose response . Control Clin Trials . 2002;23:584–603
  16. American Psychiatric Association . Diagnostic and statistical manual of mental disorders . fourth edition. Washington DC: American Psychiatric Association; 1994;
  17. Metropolitan Insurance Company . 1983 Metropolitan height and weight tables . Stat Med . 1983;64:2–9
  18. Andresen EM , Malmgren JA , Carter WB , Patrick DL . Screening for depression in well older adults (evaluation of a short form of the CES-D) . Am J Prev Med . 1994;10:77–84
  19. Taylor CB , Coffey T , Berra K , Iaffaldano R , Casey K , Haskell WL . Seven-day activity and self-report compared to a direct measure of physical activity . Am J Epidemiol . 1984;120:818–824
  20. Sallis JF , Haskell WL , Wood PD , et al.   Physical activity assessment methodology in the Five-City Project . Am J Epidemiol . 1985;121:91–106
  21. American Heart Association . Recommendations for human blood pressure determination by sphygmomanometers . Circulation . 1988;77:501A–514A
  22. American College of Sports Medicine . ACSM’s guidelines for exercise testing and prescription . 6th ed. Philadelphia: Lippincott Wiliams & Wilkins; 2000;
  23. Pate RR , Pratt M , Blair SN , et al.   Physical activity and public health. a recommendation from the Centers for Disease Control and Prevention and the American College of Sports Medicine . JAMA . 1995;273:402–407
  24. Schulz KF , Grimes DA . Allocation concealment in randomised trials (defending against deciphering) . Lancet . 2002;359:614–618
  25. The Hamilton Rating Scale for Depression . In:  McDowell I ,  Newell C editor. Measuring health (a guide to rating scales and questionnaires) . 2nd ed. New York: Oxford University Press; 1996;p. 269–276
  26. Liang KY , Zeger SL . Longitudinal data analysis using generalized linear models . Biometrika . 1986;73:13–22
  27. Elkin I , Shea MT , Watkins JT , et al.   National Institute of Mental Health Treatment of Depression Collaborative Research Program. General effectiveness of treatments . Arch Gen Psychiatry . 1989;46:971–982
  28. Martinsen EW , Hoffart A , Solberg O . Comparing aerobic with nonaerobic forms of exercise in the treatment of clinical depression (a randomized trial) . Comp Psychiatry . 1989;30:324–331

 The full text of this article is available via AJPM Online at www.ajpm-online.net.

PII: S0749-3797(04)00241-7

doi: 10.1016/j.amepre.2004.09.003

American Journal of Preventive Medicine
Volume 28, Issue 1 , Pages 1-8 , January 2005

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