Human Papillomavirus Vaccine Among Adult Women

Disparities in Awareness and Acceptance


      Human papillomavirus (HPV) vaccines have been shown to be safe and highly effective in young and middle-aged women.


      This study aimed to assess vaccine awareness and desire for vaccination among adult women aged 18–55 years residing in Los Angeles County CA.


      This study is nested in the 2007 Los Angeles County Health Survey. Included in the analyses were 2295 women aged 18–55 years. Logistic regression was used to evaluate vaccine awareness and intention to become vaccinated in association with various factors. All analyses employed weighted data and were conducted in 2009.


      Only 5% of women aged 18–26 years had received the HPV vaccine in its first year on the market. Overall, 67% of women aged 18–55 years had heard of the vaccine. Among those who knew of the vaccine but had not received it, 61% reported they were likely to receive the vaccine. Latina, black, and Asian/Pacific Islander women were only half as likely to have heard of the vaccine as white women, but Latinas and Asian/Pacific Islander women were more willing to be vaccinated than white or black women. Education was associated positively with awareness, but inversely associated with intention to be vaccinated. Awareness and desire for vaccination also varied substantially by other factors such as language spoken at home.


      This population-based study of diverse women reveals important disparities in HPV vaccine awareness and intention to be vaccinated. Culturally and linguistically competent educational campaigns about HPV immunization are warranted, and should target high-risk populations.
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        • Munoz N.
        • Manalastas Jr, R.
        • Pitisuttithum P.
        • et al.
        Safety, immunogenicity, and efficacy of quadrivalent human papillomavirus (types 6, 11, 16, 18) recombinant vaccine in women aged 24–45 years: a randomised, double-blind trial.
        Lancet. 2009; 373: 1949-1957
        • Petaja T.
        • Keranen H.
        • Karppa T.
        • et al.
        Immunogenicity and safety of human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine in healthy boys aged 10–18 years.
        J Adolesc Health. 2009; 44: 33-40
        • Yancey A.K.
        • Simon P.A.
        • McCarthy W.J.
        • Lightstone A.S.
        • Fielding J.E.
        Ethnic and sex variations in overweight self-perception: relationship to sedentariness.
        Obesity (Silver Spring). 2006; 14: 980-988
        • Yancey A.K.
        • Wold C.M.
        • McCarthy W.J.
        • et al.
        Physical inactivity and overweight among Los Angeles County adults.
        Am J Prev Med. 2004; 27: 146-152
        • Simon P.A.
        • Wold C.M.
        • Cousineau M.R.
        • Fielding J.E.
        Meeting the data needs of a local health department: the Los Angeles County Health Survey.
        Am J Public Health. 2001; 91: 1950-1952
        • The American Association for Public Opinion Research
        Standard definitions: final dispositions of case codes and outcome rates for surveys.
        5th ed. AAPOR, Lenexa KS2008
        • Freeman H.P.
        • Wingrove B.K.
        Excess cervical cancer mortality: a marker for low access to health care in poor communities.
        National Cancer Institute, Center to Reduce Cancer Health Disparities, Rockvillle MD2005
        • Jain N.
        • Euler G.L.
        • Shefer A.
        • Lu P.
        • Yankey D.
        • Markowitz L.
        Human papillomavirus (HPV) awareness and vaccination initiation among women in the U.S., National Immunization Survey—Adult 2007.
        Prev Med. 2009; 48: 426-431
        • Los Angeles County Department of Health Services, Immunization Program
        Immunization barriers in African American communities: discussions with parents and guardians.
        LACDHS, Los Angeles CA2005
        • Sengupta S.
        • Corbie-Smith G.
        • Thrasher A.
        • Strauss R.P.
        African American elders' perceptions of the influenza vaccine in Durham, North Carolina.
        N C Med J. 2004; 65: 194-199