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Influenza A (H1N1) 2009 Monovalent Vaccination Among Adults with Asthma, U.S., 2010

      Background

      The 2009 pandemic influenza A (H1N1) virus (2009 H1N1) was first identified in April 2009 and quickly spread around the world. The first doses of influenza A (H1N1) 2009 monovalent vaccine (2009 H1N1 vaccine) became available in the U.S. in early October 2009. Because people with asthma are at increased risk of complications from influenza, people with asthma were included among the initial prioritized groups.

      Purpose

      To evaluate 2009 H1N1 vaccination coverage and identify factors independently associated with vaccination among adults with asthma in the U.S.

      Methods

      Data from the 2009–2010 BRFSS (Behavioral Risk Factor Surveillance System) influenza supplemental survey were used; responses from March through June 2010 were analyzed to estimate vaccination levels of 2009 H1N1 vaccine among respondents aged 25–64 years with asthma. Multivariable logistic regression and predictive marginal models were performed to identify factors independently associated with vaccination.

      Results

      Among adults aged 25–64 years with asthma, 25.5% (95% CI=23.9%, 27.2%) received the 2009 H1N1 vaccination. Vaccination coverage ranged from 9.9% (95% CI=6.4%, 15.1%) in Mississippi to 46.1% (95% CI=33.3%, 61.2%) in Maine. Characteristics independently associated with an increased likelihood of vaccination among adults with asthma were as follows: had a primary doctor, had other high-risk conditions, and received seasonal influenza vaccination in the 2009–2010 season.

      Conclusions

      Vaccination coverage among adults aged 25–64 years with asthma was only 25.5% and varied widely by state and demographic characteristics. National and state-specific 2009 H1N1 vaccination coverage data for adults with asthma are useful for evaluating the vaccination campaign and for planning and implementing strategies for increasing vaccination coverage in possible future pandemics.
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      References

        • Moorman J.E.
        • Rudd R.A.
        • Johnson C.A.
        • et al.
        Centers for Disease Control and Prevention (CDC).
        MMWR Surveill Summ. 2007; 56: 1-54
        • CDC
        Summary health statistics for U.S. children: National Health Interview Survey, 2008.
        Vital Health Stat. 2009; 244: 1-81
        • CDC
        Summary health statistics for U.S. adults: National Health Interview Survey, 2008.
        Vital Health Stat 10. 2009; 242: 1-157
      1. CDC, National Center for Health Statistics.
        Natl Health Stat Report. 2011; 32: 1-14
        • Ford E.S.
        • Williams S.G.
        • Mannino D.M.
        • Redd S.C.
        Influenza vaccination coverage among adults with asthma.
        Am J Med. 2004; 116: 555-558
        • Teichtahl H.
        • Buckmaster N.
        • Pertnikovs E.
        The incidence of respiratory tract infection in adults requiring hospitalization for asthma.
        Chest. 1997; 112: 591-596
        • Atmar R.L.
        • Guy E.
        • Guntupalli
        • et al.
        Respiratory tract viral infections in inner-city asthmatic adults.
        Arch Intern Med. 1998; 158: 2453-2459
        • Neuzil K.M.
        • Wright P.F.
        • Mitchel Jr, E.F.
        • Griffin M.R.
        The burden of influenza illness in children with asthma and other chronic medical conditions.
        J Pediatr. 2000; 137: 856-864
        • CDC
        Prevention and control of influenza: recommendations of the Advisory Committee on Immunization Practices (ACIP), 2010.
        MMWR Recomm Rep. 2010; 59: 1-62
        • National Asthma Education and Prevention Program
        Expert panel report 3: guidelines for the diagnosis and management of asthma.
        NIH, National Heart, Lung, and Blood Institute, Bethesda MD2007 (www.nhlbi.nih.gov/guidelines/asthma/)
        • Williams S.G.
        • Schmidt D.K.
        • Redd S.C.
        • Storms W.
        Key clinical activities for quality asthma care: recommendations of the National Asthma Education and Prevention Program.
        MMWR Recomm Rep. 2003; 52: 1-8
        • CDC
        Use of influenza A (H1N1) 2009 monovalent vaccine: recommendations of the Advisory Committee on Immunization Practices (ACIP), 2009.
        MMWR Recomm Rep. 2009; 58: 1-8
        • CDC
        Update on Influenza A (H1N1) 2009 monovalent vaccines.
        MMWR Morb Mortal Wkly Rep. 2009; 58: 1100-1101
        • CDC
        2009 BRFSS Summary Data Quality Report.
        DHHS, CDC, Atlanta GA2009 (www.cdc.gov/brfss/technical_infodata/surveydata/2009.htm)
        • Korn E.L.
        • Graubard B.I.
        • Analysis of health surveys
        Predictive margins (direct standardization).
        in: John Wiley & Sons, New York NY1999: 126-140
        • Nadel M.R.
        • Shapiro J.A.
        • Klabunde C.N.
        • et al.
        A national survey of primary care physicians' methods for screening for fecal occult blood.
        Ann Intern Med. 2005; 142: 86-94
        • Egede L.E.
        • Zheng D.
        Racial/ethnic differences in influenza vaccination coverage in high-risk adults.
        Am J Public Health. 2003; 93: 2074-2078
        • Lu P.J.
        • Euler G.L.
        • Callahan D.B.
        Influenza vaccination among adults with asthma: findings from the 2007 BRFSS survey.
        Am J Prev Med. 2009; 37: 109-115
        • CDC
        National influenza vaccination week—January 10–16, 2010.
        MMWR Morb Mortal Wkly Rep. 2010; 58: 1444
        • CDC
        Update: Influenza activity—U.S., August 30, 2009-March 27, 2010, and composition of the 2010–11 influenza vaccine.
        MMWR Morb Mortal Wkly Rep. 2010; 59: 423-430
        • CDC
        Update: Influenza activity—U.S., August 30, 2009-January 9, 2010.
        MMWR Morb Mortal Wkly Rep. 2010; 59: 38-43
        • CDC
        Interim results: influenza A (H1N1) 2009 monovalent vaccination coverage—U.S., October–December 2009.
        MMWR Morb Mortal Wkly Rep. 2010; 59: 44-48
        • Maurer J.
        • Uscher-Pines L.
        • Harris K.M.
        Awareness of government seasonal and 2009 H1N1 influenza vaccination recommendations among targeted US adults: the role of provider interactions.
        Am J Infect Control. 2010; 38: 489-490
        • Blumberg S.J.
        • Luke J.V.
        Reevaluating the need for concern regarding non-coverage bias in landline surveys.
        Am J Public Health. 2009; 99: 1806-1810
        • CDC
        Interim Results: State-Specific Seasonal Influenza Vaccination Coverage—U.S., August 2009–January 2010.
        MMWR Morb Mortal Wkly Rep. 2010; 59: 447-484