Background
Associations of sitting-time and physical activity with depression are unclear.
Purpose
To examine concurrent and prospective associations between both sitting-time and physical
activity with prevalent depressive symptoms in mid-aged Australian women.
Methods
Data were from 8950 women, aged 50–55 years in 2001, who completed mail surveys in
2001, 2004, 2007, and 2010. Depressive symptoms were assessed using the Center for
Epidemiological Studies Depression questionnaire. Associations between sitting-time
(≤4 hours/day, >4–7 hours/day, >7 hours/day) and physical activity (none, some, meeting
guidelines) with depressive symptoms (symptoms/no symptoms) were examined in 2011
in concurrent and lagged mixed-effect logistic modeling. Both main effects and interaction
models were developed.
Results
In main effects modeling, women who sat >7 hours/day (OR=1.47, 95% CI=1.29, 1.67)
and women who did no physical activity (OR=1.99, 95% CI=1.75, 2.27) were more likely
to have depressive symptoms than women who sat ≤4 hours/day and who met physical activity
guidelines, respectively. In interaction modeling, the likelihood of depressive symptoms
in women who sat >7 hours/day and did no physical activity was triple that of women who sat ≤4 hours/day and met physical activity guidelines (OR 2.96, 95% CI=2.37, 3.69). In prospective main
effects and interaction modeling, sitting-time was not associated with depressive
symptoms, but women who did no physical activity were more likely than those who met
physical activity guidelines to have future depressive symptoms (OR=1.26, 95% CI=1.08,
1.47).
Conclusions
Increasing physical activity to a level commensurate with guidelines can alleviate
current depression symptoms and prevent future symptoms in mid-aged women. Reducing
sitting-time may ameliorate current symptoms.
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© 2013 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.