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Sex of Sexual Partners and Human Papillomavirus Vaccination Among U.S. Girls and Women

  • Madina Agénor
    Correspondence
    Address correspondence to: Madina Agénor, ScD, MPH, Department of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, 677 Huntington Avenue, Kresge Building 7th Floor, Boston MA 02115
    Affiliations
    Department of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, Massachusetts

    Center for Community-Based Research, Dana Farber Cancer Institute, Boston, Massachusetts
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  • Heather L. McCauley
    Affiliations
    Division of Adolescent Medicine, Children’s Hospital of Pittsburgh, Pittsburgh, Pennsylvania

    Division of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania
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  • Sarah M. Peitzmeier
    Affiliations
    Department of Population, Family and Reproductive Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland
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  • Sebastien Haneuse
    Affiliations
    Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts
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  • Allegra R. Gordon
    Affiliations
    Division of Adolescent and Young Adult Medicine, Boston Children’s Hospital, Boston, Massachusetts

    Department of Pediatrics, Harvard Medical School, Boston, Massachusetts
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  • Jennifer Potter
    Affiliations
    Department of Medicine, Harvard Medical School, Boston, Massachusetts

    Women’s Health Program, Fenway Health, Boston, Massachusetts

    Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts
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  • S. Bryn Austin
    Affiliations
    Department of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, Massachusetts

    Division of Adolescent and Young Adult Medicine, Boston Children’s Hospital, Boston, Massachusetts

    Department of Pediatrics, Harvard Medical School, Boston, Massachusetts
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Published:November 12, 2015DOI:https://doi.org/10.1016/j.amepre.2015.08.025

      Introduction

      Girls and women are at risk of human papillomavirus (HPV) infection and cervical cancer from male and female sexual partners throughout the life course. However, no study has assessed how sex of sexual partners, a dimension of sexual orientation, may relate to HPV vaccination among girls and women.

      Methods

      In 2014, data from the 2006–2010 National Survey of Family Growth were used to conduct logistic regression analyses estimating the relationship between sex of lifetime and past-year sexual partners and HPV vaccine awareness and initiation among U.S. girls and women aged 15–25 years (N=3,253).

      Results

      Among U.S. girls and women aged 15–25 years, the prevalence of HPV vaccine awareness and HPV vaccine initiation was 84.4% and 28.5%, respectively. Adjusting for sociodemographic factors, participants with only female past-year sexual partners had significantly lower odds of initiating HPV vaccination relative to those with only male past-year sexual partners (OR=0.16, 95% CI=0.05, 0.55). Similarly, respondents with no lifetime (OR=0.65, 95% CI=0.46, 0.92) or past-year (OR=0.69, 95% CI=0.50, 0.94) sexual partners had significantly lower adjusted odds of HPV vaccine initiation compared with those with only male sexual partners. No difference was apparent in the odds of initiating HPV vaccination between participants with male and female sexual partners and those with only male sexual partners.

      Conclusions

      Medical and public health professionals should ensure that girls and women with only female or no sexual partners are included in HPV vaccine education and promotion efforts.
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