The development of vaccines that could provide broad protection against antigenically
variant influenza viruses has long been the ultimate prize in influenza research.
Recent developments have pushed us closer to this goal, and such vaccines may now
be within reach. This brief review outlines the current approaches to broadly protective
vaccines, and the probable hurdles and roadblocks to achieving this goal.
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© 2015 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.
