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HHS, NIH, National Institute on Drug Abuse. Research Report: Misuse of Prescription Drugs. www.drugabuse.gov/publications/research-reports/misuse-prescription-drugs/summary. Updated January 2018. Accessed June 3, 2018.
HHS, Food and Drug Administration, Center for Drug Evaluation and Research. Assessment of abuse potential of drugs—guidance for industry. www.fda.gov/downloads/drugs/guidancecomplianceregulatoryinformation/guidances/ucm198650.pdf. Updated January 2018. Accessed June 4, 2018.
- Increasing deaths from opioid analgesics in the United States.Pharmacoepidemiol Drug Saf. 2006; 15: 618-627
- HHS Acting secretary declares public health emergency to address national opioid crisis [press release].www.hhs.gov/about/news/2017/10/26/hhs-acting-secretary-declares-public-health-emergency-address-national-opioid-crisis.html(Published 2017 Updated April 24, 2018. Accessed December 16,)Date: 2018
HHS, Centers for Disease Control and Prevention (CDC), National Center for Health Statistics. Multiple Cause of Death 1999–2016 on CDC WONDER Online Database. http://wonder.cdc.gov/mcd-icd10.html. Updated December 2017. Accessed March 30, 2018.
HHS, NIH, National Institute on Drug Abuse. Opioid involvement in benzodiazepine overdose. www.drugabuse.gov/related-topics/trends-statistics/overdose-death-rates. Updated September 2017. Accessed March 30, 2018.
- Our other prescription drug problem.N Engl J Med. 2018; 378: 693-695
- Physician prescribing of opioids to patients at increased risk of overdose from benzodiazepine use in the United States.JAMA Psychiatry. 2018; 75: 623-630
- Trends in the concomitant prescribing of opioids and benzodiazepines, 2002–2014.Am J Prev Med. 2016; 51: 151-160
- Emergency department visits and overdose deaths from combined use of opioids and benzodiazepines.Am J Prev Med. 2015; 49: 493-501
- Vital signs: trends in emergency department visits for suspected opioid overdoses—United States, July 2016–September 2017.MMWR Morb Mortal Wkly Rep. 2018; 67: 279-285
- Evaluation and overview of the National Electronic Injury Surveillance System–Cooperative Adverse Drug Event Surveillance Project (NEISS-CADES).Med Care. 2007; 45: S96-S102
Schroeder T, Ault K. The NEISS sample (design and implementation) 1997 to present. www.cpsc.gov//PageFiles/106617/2001d011-6b6.pdf. Updated June 1, 2001. Accessed March 28, 2018.
U.S. Consumer Product Safety Commission. NEISS—The National Electronic Injury Surveillance System: a tool for researchers. www.cpsc.gov/PageFiles/106626/2000d015.pdf. Updated March 2000. Accessed October 1, 2018.
- Distinguishing public health research and public health nonresearch.www.cdc.gov/od/science/integrity/docs/cdc-policy-distinguishing-public-health-research-nonresearch.pdf(Published 2010 Updated July 31, 2018. Accessed December 16,)Date: 2018
- Things that work, things that don't work, and things that matter—including words.J Addict Med. 2015; 9: 429-430
- Language and addiction: choosing words wisely.Am J Public Health. 2013; 103: e1-e2
- Trends in medical use of opioids in the U.S., 2006–2016.Am J Prev Med. 2018; 54: 652-660
- Prescription opioid use, misuse, and use disorders in U.S. adults: 2015 National Survey on Drug Use and Health.Ann Intern Med. 2017; 167: 293-301
- Identifying injection drug users at risk of nonfatal overdose.Acad Emerg Med. 2007; 14: 616-623
- Opioid prescribing after nonfatal overdose and association with repeated overdose: a cohort study.Ann Intern Med. 2016; 164: 1-9
- Causes of death after nonfatal opioid overdose.JAMA Psychiatry. 2018; 75: 820-827
- Combatting opioid overdoses in Ohio: emergency department physicians’ prescribing patterns and perceptions of naloxone.J Gen Intern Med. 2018; 33: 608-609
HHS, Office of the Surgeon General. Surgeon General's advisory on naloxone and opioid overdose. www.surgeongeneral.gov/priorities/opioid-overdose-prevention/naloxone-advisory.html. Updated April 2018. Accessed May 1, 2018.
- CDC guideline for prescribing opioids for chronic pain – United States, 2016.MMWR Recomm Rep. 2016; 65: 1-49
- A pilot randomized clinical trial of an intervention to reduce overdose risk behaviors among emergency department patients at risk for prescription opioid overdose.Drug Alcohol Depend. 2016; 163: 40-47
- Behavioral intervention to reduce opioid overdose among high-risk persons with opioid use disorder: a pilot randomized controlled trial.PLoS One. 2017; 12e0183354.
- Emergency department-initiated buprenorphine for opioid dependence with continuation in primary care: outcomes during and after intervention.J Gen Intern Med. 2017; 32: 660-666
- Medication for opioid use disorder after nonfatal opioid overdose and association with mortality: a cohort study.Ann Intern Med. 2018; 169: 137-145
- Overdose prevention through medical treatment of opioid use disorders.Ann Intern Med. 2018; 169: 190-192
HHS, Food and Drug Administration. FDA's opioid analgesic REMS education blueprint for health care providers involved in the treatment and monitoring of patients with pain (revised FDA blueprint). www.regulations.gov/contentStreamer?documentId=FDA-2017-D-2497-0683&attachmentNumber=1&contentType=pdf. Updated January 2018. Accessed May 3, 2018.
HHS, Substance Abuse and Mental Health Services Administration and Health Resources and Services Administration. Drug & alcohol use screening tools. www.integration.samhsa.gov/clinical-practice/screening-tools#drugs. Updated 2018. Accessed May 11, 2018.
- Treatment of benzodiazepine dependence.N Engl J Med. 2017; 376: 1147-1157
HHS, Substance Abuse and Mental Health Services Administration and Health Resources and Services Administration. Safe & effective use of benzodiazepines in clinical practice. www.integration.samhsa.gov/about-us/Benzodiazepines_Presentation.pdf. Updated May 2017. Accessed May 16, 2018.
- Misuse and abuse of pregabalin and gabapentin: cause for concern?.CNS Drugs. 2014; 28: 491-496
- Abuse and misuse of pregabalin and gabapentin.Drugs. 2017; 77: 403-426
- The FDA and the next wave of drug abuse: proactive pharmacovigilance.N Engl J Med. 2018; 379: 205-207
Gottlieb S. Emerging issues of misuse and abuse of OTC loperamide challenge FDA to address a new turn in the opioid addiction crisis, while maintaining access for patients. https://blogs.fda.gov/fdavoice/index.php/2018/05/emerging-issues-of-misuse-and-abuse-of-otc-loperamide-challenge-fda-to-address-a-new-turn-in-the-opioid-addiction-crisis-while-maintaining-access-for-patients/. Updated May 2018. Accessed May 13, 2018.
HHS, Food and Drug Administration. FDA Drug Safety Communication: FDA limits packaging for anti-diarrhea medicine loperamide (Imodium) to encourage safe use. www.fda.gov/Drugs/DrugSafety/ucm594232.htm. Updated January 2018. Accessed May 14, 2018.
- Pediatric ADHD medication exposures reported to U.S. poison control centers.Pediatrics. 2018; 141e20173872.
- Suicide: a silent contributor to opioid-overdose deaths.N Engl J Med. 2018; 378: 1567-1569
- Opioid prescriptions for chronic pain and overdose: a cohort study.Ann Intern Med. 2010; 152: 85-92
- Classifying nonsuicidal overdoses: nonsuicidal self-injury, suicide attempts, or neither?.Psychiatry Res. 2016; 244: 235-242